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K-20 Progesterone K-20 Progesterone PROGESTERONE is a highly absorbable sublingual solution of pregesterone. Sublingual hormones avoid the first liver pass, which decreases their conversion to other hormones and metabolites. Consider this whenever natural progesterone augmentation is required such as maintaining a healthy estrogen to progesterone balance. Symptoms of low progesterone include: heavy menstruation with increased bleeding, depression, low libido and inability to lose weight.
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